Making sense of CBG (Cannabigerol) & what the cannabis cannabinoid does?

Making sense of CBG (Cannabigerol) & what the cannabis cannabinoid does?

CBG and its psychoactive roles


CBG or Cannabigerol is a minor nonpyschoactive phytocannabinoid found in high-CBD and low-THC strains of cannabis. Cannabinoids are broadly classified as phytocannabinoids, endogenous molecules or endocannabinoid and synthetic cannabinoids. The compounds have the ability to alter different body functions. According to Frontiers in Pharmacology findings published by NCBI, cannabinoid compounds like CBG produce varied responses by binding and triggering Cannabinoid receptor type I (CB1) and Cannabinoid receptor type II (CB2).

For instance, to prevent the high effects of THC, CBG acts as a Cannabinoid receptor type 1 (CB1) antagonist. According to Cresco Laboratories, CBG acts by creating a perfect buffer for THC psychoactivity. The resultant effect can help alleviate paranoia, pain, inflammation and the spread of certain cancers. The other powerful effect is the ability to trigger the release of anandamide, an essential Omega-6 fatty acid responsible for happiness in the brain. Marijuana contains more than 100 cannabinoids, including THC (Tetrahydrocannabinol) and CBD (Cannabidiol).

Cannabigerol potential medical benefits?


Interest in researching the less known cannabis cannabinoids is growing in the US due to the advances in technology, growing appreciation for cannabis cannabinoids and relaxed legislations. Some of studies tout CBG as one of the most promising Cannabinoids because of its potential health benefits. The phytocannabinoid is currently being used to treat the following conditions and symptoms;

1. Glaucoma
CBG has long been used to treat and manage Glaucoma. The eye condition is caused by damage to the optic nerve as a result of internal pressure buildup. Cannabigerol works by reducing the amount of intraocular pressure impacting the eye. A 1990 study published by the National center for Biotechnology Information (NCBI) suggests CBG has therapeutic potential to provide relief to glaucoma sufferers. The cannabinoid can be safely taken with other prescription medications, but this should only be done after consulting a doctor.

2. Cancer
Cannabinoids have been shown to possess anti-tumor properties capable of fighting cancer. An oncological study carried out in 2014 suggests Cannabigerol can inhibit carcinogenesis or the formation of cancerous cells. The analysis was obtained from a study of mice with colorectal cancer.

3. Crohn’s disease
CBG has been found useful in the treatment of Crohn’s disease. According to GHmedical, preclinical evidence suggests a select group of cannabinoids that includes CBG possess anti-inflammatory properties that can treat or suppress the symptoms of Crohn’s disease. The chronic disease affects the digestive track. Its symptoms include severe diarrhea, skin rash and abdominal pain.

4. Irritable Bowel Syndrome (IBS)
The calming effect of Cannabigerol can help ease Irritable Bowel Syndrome. The revelations come from a 2018 study by a team of researchers from the University of Bath. The team analyzed the effects of natural cannabinoids in the endocannabinoid system in fighting IBS. An earlier study also found the compound to be effective in fighting inflammation of the colon in mice. The success of 2013 study prompted researchers to turn their sights on Irritable Bowel Syndrome in humans.

Other medical benefits of the Cannabigerol CBG

The study of the medical benefits of CBG in treating anxiety and depression, bladder disorders, cancer and other diseases is ongoing. The cannabinoid is also suggested to have neuro-protective properties, which could offer relief to people suffering from degenerative brain diseases. One of the diseases is the Huntington’s disease, which is a deadly form of genetic disorder that causes progressive breakdown of the nerve cells found in the brain. The only limitations that may affect the full exploitation of Cannabigerol’s medical and health benefits are the restrictions placed on the marijuana testing. The US government through the National Center for Complimentary and Integrative Health (NCCIH) has, however, taken an interest in studying the effects of Cannabigerol in physiological processes and pain management.

How is CBG Made?

Cannabigerol is a known non-psychotropic cannabinoid derived from CBGA (Cannabigerolic Acid) through the biosynthesis process. Cannabigerolic Acid is often referred to as the mother of all marijuana cannabinoids. The enzymes found in the marijuana plant act by breaking down CBGA into various cannabinoids, including THC and CBD. The composition of CGA on most strains of cannabis is normally 1 percent or lower. In spite of the low levels of concentration, Cannabigerol still plays a definitive role in the endocannabinoid system (ECS) due to its ability to interact with the cannabinoid receptors. Its overall effects are, however, subdued compared to those of the CBD and more so, THC. The latter stands out as the most psychoactive marijuana cannabinoid.

To obtain higher Cannabigerol concentrations, marijuana breeders are increasingly looking at crossbreeding and genetic phyto-engineering of the least known cannabinoids. Marijuana strains that are nipped in the bud are also said to contain higher concentrations of CBG. A number of companies are spearheading the initiative and in the process extracting high volumes of the non-intoxicating compound. A body of research also suggests high volumes of Cannabigerol can be obtained from industrial hemp and high yield Cannabigerol cannabis oils. In spite of the advances in bio-technology, the cost of producing Cannabigerol remains largely prohibitive because the equipment’s required to perform procedures like chromatography are very expensive.

Learn more about Cannabinoids

CBG has been shown to boost the production of natural chemicals found in the brain. The compound offers several medical benefits that can be used to treat various conditions, including depression and anxiety. It is important to pinpoint that Cannabigerol is currently not listed as a controlled substance since the components used in production are not controlled. If you want to learn more about Cannabigerol and other cannabinoids like CBD, visit CBD Discount Shop.

The site also sells high quality CBD and Cannabigerol products. The CBD products offer relief for pain, sleep and anxiety. All orders purchased from CBD Discount Shop takes between 1 to 3 days to be submitted. The timelines may vary depending on where the order is being sent. All the orders that are dispatched are accompanied by an email containing parcel tracking information. The company runs a highly rewarding affiliate program to encourage partners and buyers.
Next article CBD Oil's Benefits for Skin: Can it Help With Acne, Anti-Aging, & Other Skin Issues?
the importance of social proof